The goal of this study is to offer an overview of the phenotypes of preschool wheezing that have been found. Early wheezing patterns have been documented in numerous populations, with some similarities discovered between cohorts. Environmental exposures in early childhood have been revealed to be variably linked with preschool wheeze traits and their subsequent trajectories. These include allergy and microbial exposure, cigarette smoke exposure in the environment, and maternal stress and depression. Elevated IgE levels in childhood may also impact future asthma risk.

Preschool wheeze phenotypes are varied and complicated, with trajectories linked to variables such as environmental exposures. More study is required to describe these associations, which will hopefully lead to tailored preventative interventions.

Reference: https://journals.lww.com/co-allergy/Abstract/2019/04000/Phenotypes_of_wheezing_and_asthma_in_preschool.12.aspx

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