Grief does not only affect human emotions but also impacts their physical health. Understanding the people’s physical suffering can bring the grip of its daunting nature, a situation where routines become challenging. Researchers used a qualitative explorative, descriptive research method.

Researchers used a purposive sample of 18 ward supervisors and 39 ward midwives to ascertain maternal deaths’ physical effects on these caregivers in the Ashanti Region of Ghana. Data were collected through semistructured and focus group discussions. Researchers did data analysis parallel with data collection till Researchers reached saturation. Ethics was obtained from the University of the Western Cape, South Africa, and Ghana Health Service. The findings indicated that generally, as a result of grieving over their patients’ deaths, midwives experienced physical health sufferings.

Therefore, the present study reported that depression is expressed as insomnia, appetite loss, exhaustion, and social isolation. There is a need to reduce the physical effects of patients’ death on caregivers in Ghana. Therefore, the study recommends that all hospitals in Ghana utilize employee assistance programs, a workplace intervention program designed for such purposes.