Patients with renal failure due to multiple myeloma (MM) who underwent kidney transplant (KT) had equivalent graft and age-matched overall survival (OS) compared with the general KT population, according to a study published in Clinical Lymphoma, Myeloma and Leukemia. Kaitlyn Dykes, MD, BS, and colleagues analyzed data from the Organ Procurement and Transplantation Network/National United Network for Organ Sharing (OPTON/ UNOS). In addition, researchers evaluated the 2013-2017 United States Renal Data System (USRDS) for incidence and mortality of MM end-stage renal disease (ESRD). They found that 961 patients diagnosed with ESRD due to MM accounted for 0.8% of the ESRD population. Among patients with MM who did not undergo KT, 44.4% died in the first year of initiating renal replacement. No difference was found in graft survival between patients with MM and the general population. A higher risk for death was observed in patients with KT with MM, and median OS was 8.4 years; however, survival differences did not exist among patients aged 50 or older.
