Over the past years, the number of women approaching childbearing age after arterial switch surgery for transposition of the great arteries is increasing. The objective of this study is to evaluate pregnancy outcomes in women with transposition of the great arteries after an arterial switch operation.

This cohort study included a total of 25 pregnancies in 15 women aged 16 years or older who had arterial switch surgery for transposition of the great arteries. The included women were assessed before, during, and after pregnancy. The primary outcomes of the study included adverse maternal cardiac events, including arrhythmia, heart failure, aortic dissection, or acute coronary syndrome, along with aortic regurgitation, aortic root dilatation, and left ventricular function before and after pregnancy.

 Among 15 women included in the study, 8 had 1 pregnancy, and 7 were multiparous. No adverse maternal cardiac events were reported during the study. Before pregnancy, 8 women (53%) had no aortic regurgitation, 1 (7%) had insignificant regurgitation, 4 (26%) experienced mild regurgitation, and 2 (14%) reported moderate regurgitation.

 The research concluded that pregnancy was well-tolerated in women with transposition of the great arteries after arterial switch surgery, with no risk of adverse cardiac events.

Ref: https://jamanetwork.com/journals/jamacardiology/fullarticle/2698939?resultClick=1+