The OSA is commonly found in ILD with overall incidence varying from 17 to 88 %. The morbidity and mortality of OSA are high when it occurs with chronic respiratory diseases like ILD. There is lack of data on sleep breathing disorder in ILD patients from India. The present study aims is to assess the occurrence of OSA in ILD patients and its correlation with other parameters.
Prospective observational study of 41 ILD patients of one year duration. All patients underwent detailed clinical examination, radiological, laboratory investigations and Type 1 diagnostic polysomnography according to AASM guideline. The severity of OSA was defined as per AHI and the correlation of OSA with other parameters were assessed.& & Result: The mean age was 55.5±10years with 73% female. The mean BMI of 28.8±6.5 kg/m2 with dyspnea and cough were the common symptoms. The most common type of ILD was HP (46.3%). The common HRCT findings were GGO (82.9%), and fibrosis (65.9%). The OSA was seen in 32(78%) patients with 24 females. The AHI showed significant positive correlation with BMI (p=0.000, r= 0.535) and ODI (p=0.000, r=0.725), while negative correlation with FEV1 /FVC% (p=0.007, r= -0.417).
The prevalence of OSA is common in north Indian ILD patients. Polysomnography should be done in all the patients with ILD whenever feasible for early diagnosis and treatment of OSA, as the coexisting of both will further decrease quality of life and increase morbidity in this chronic progressive lung disease.
© Journal of the Association of Physicians of India 2011.
About The Expert
Tome Kamgo
Sonam Spalgais
Raj Kumar
References
PubMed