In 1999, the American Heart Association (AHA) published its first Guide to Preventive Cardiology in Women. The guide synthesized the most recent clinical research data and highlighted unique aspects of risk factor management in women. Subsequently, in 2003, a systematic review was conducted, and evidence-based guidelines for the prevention of cardiovascular disease (CVD) in women were released. Since that time, numerous clinical trials have been conducted to evaluate differences that exist between men and women in relation to CVD diagnosis and prevention.

A 2007 guideline update provides the most current clinical recommendations for preventing CVD in women aged 20 and older. They are based on a systematic search of the highest quality science interpreted by experts in the fields of cardiology, epidemiology, family medicine, gynecology, internal medicine, neurology, nursing, public health, statistics, and surgery. The 2007 Guidelines for Preventing Cardiovascular Disease in Women were published in a special women