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Prognostic Factors of Human Immunodeficiency Virus-Infected Patients on Chronic Hemodialysis.

Prognostic Factors of Human Immunodeficiency Virus-Infected Patients on Chronic Hemodialysis.
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Laranjinha I, João Matias P, Dickson J, Estibeiro H, Boquinhas H, Barata JD,


Laranjinha I, João Matias P, Dickson J, Estibeiro H, Boquinhas H, Barata JD, (click to view)

Laranjinha I, João Matias P, Dickson J, Estibeiro H, Boquinhas H, Barata JD,

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Blood purification 2017 10 0344(3) 244-250 doi 10.1159/000478966

Abstract
BACKGROUND/AIMS
The number of human immunodeficiency virus (HIV)-infected patients on hemodialysis (HD) have increased, and their prognostic factors are still poorly clarified. The study aimed to identify factors that can influence the survival of HIV-infected patients on HD.

METHODS
We performed a retrospective cohort study of 44 HIV-infected patients on HD.

RESULTS
A total of 17 patients (39%) died. Median survival on HD was 30.8 months and the survival rate at 1 and 5 years was 82.5 and 62.9%, respectively. Male (relative risk [RR] 3.1, p = 0.040) and blacks (RR 2.5, p = 0.037) had higher risk of death. The patients who died had a shorter duration of HIV infection (p = 0.028), had a higher viral load (p = 0.044), more opportunistic infections (p = 0.013), and a lower serum albumin (p = 0.009). Lower serum albumin, nonsexual HIV transmission, viral load, opportunistic infections, and usage of catheters were associated with lower survival.

CONCLUSION
Several demographic, viral, and dialysis variables may help to predict survival of this population. The intervention in these factors could improve their prognosis.

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