The following is a summary of “Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury,” published in the November 2023 issue of Nephrology by Vieira et al.
Regional citrate anticoagulation (RCA) has been proposed as an alternative to heparin for prolonged hemodialysis (HD), but its use may be associated with challenges in patient management and HD completion.
Researchers evaluated the safety and effectiveness of prolonged hemodialysis using regional citrate anticoagulation with a 4% sodium citrate solution in a Genius® hybrid system.
They conducted the study in an intensive care unit. The results showed that 53 random sessions of prolonged HD using a 4% sodium citrate solution were conducted in critically ill patients with acute kidney injury (AKI). Safety indicators included dysnatremia (15%) and metabolic alkalosis (9.4%). Effectiveness indicators revealed system clotting in 17.3% of sessions and a minimum completion rate of 75.5% for the prescribed HD time.
Investigators concluded Prolonged hemodialysis with regional citrate anticoagulation using the Genius system was safe and effective in critically ill patients with acute kidney injury.
Source: bmcnephrol.biomedcentral.com/articles/10.1186/s12882-023-03342-8
