Advertisement

 

 

Racial disparities in the prevalence and control of hypertension among a cohort of HIV-infected patients in the southeastern United States.

Racial disparities in the prevalence and control of hypertension among a cohort of HIV-infected patients in the southeastern United States.
Author Information (click to view)

Burkholder GA, Tamhane AR, Safford MM, Muntner PM, Willig AL, Willig JH, Raper JL, Saag MS, Mugavero MJ,


Burkholder GA, Tamhane AR, Safford MM, Muntner PM, Willig AL, Willig JH, Raper JL, Saag MS, Mugavero MJ, (click to view)

Burkholder GA, Tamhane AR, Safford MM, Muntner PM, Willig AL, Willig JH, Raper JL, Saag MS, Mugavero MJ,

Advertisement

PloS one 2018 03 2913(3) e0194940 doi 10.1371/journal.pone.0194940

Abstract
BACKGROUND
African Americans are disproportionately affected by both HIV and hypertension. Failure to modify risk factors for cardiovascular disease and chronic kidney disease such as hypertension among HIV-infected patients may attenuate the benefits conferred by combination antiretroviral therapy. In the general population, African Americans with hypertension are less likely to have controlled blood pressure than whites. However, racial differences in blood pressure control among HIV-infected patients are not well studied.

METHODS
We conducted a cross-sectional study evaluating racial differences in hypertension prevalence, treatment, and control among 1,664 patients attending the University of Alabama at Birmingham HIV Clinic in 2013. Multivariable analyses were performed to calculate prevalence ratios (PR) with 95% confidence intervals (CI) as the measure of association between race and hypertension prevalence and control while adjusting for other covariates.

RESULTS
The mean age of patients was 47 years, 77% were male and 54% African-American. The prevalence of hypertension was higher among African Americans compared with whites (49% vs. 43%; p = 0.02). Among those with hypertension, 91% of African Americans and 93% of whites were treated (p = 0.43). Among those treated, 50% of African Americans versus 60% of whites had controlled blood pressure (systolic blood pressure <140 mmHg and diastolic blood pressure <90 mmHg) (p = 0.007). After multivariable adjustment for potential confounders, prevalence of hypertension was higher among African Americans compared to whites (PR 1.25; 95% CI 1.12-1.39) and prevalence of BP control was lower (PR 0.80; 95% CI 0.69-0.93). CONCLUSIONS
Despite comparable levels of hypertension treatment, African Americans in our HIV cohort were less likely to achieve blood pressure control. This may place them at increased risk for adverse outcomes that disproportionately impact HIV-infected patients, such as cardiovascular disease and chronic kidney disease, and thus attenuate the benefits conferred by combination antiretroviral therapy.

Submit a Comment

Your email address will not be published. Required fields are marked *

2 + three =

[ HIDE/SHOW ]