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Radiofrequency ablation for liver metastases in patients with gastric cancer as an alternative to hepatic resection.

Radiofrequency ablation for liver metastases in patients with gastric cancer as an alternative to hepatic resection.
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Lee JW, Choi MH, Lee YJ, Ali B, Yoo HM, Song KY, Park CH,


Lee JW, Choi MH, Lee YJ, Ali B, Yoo HM, Song KY, Park CH, (click to view)

Lee JW, Choi MH, Lee YJ, Ali B, Yoo HM, Song KY, Park CH,

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BMC cancer 2017 03 1017(1) 185 doi 10.1186/s12885-017-3156-1
Abstract
BACKGROUND
The purpose of this retrospective study was to determine whether RFA could provide an alternative treatment modality for selected patients who are not candidates for hepatic resection.

METHODS
A total of 18 consecutive patients with liver metastases alone from gastric cancer treated with radiofrequency ablation (RFA, n = 11) or hepatic resection (HR, n = 7) at Seoul St. Mary’s Hospital, Korea, between January 2000 and September 2014, were enrolled.

RESULTS
The median OS and DFS in the RFA group were 40.5 ± 22.3 and 10.3 ± 1.07 months, respectively. There was no significant difference between the RFA and HR groups in terms of baseline characteristics except for performance status. Mean survival and DFS times of all patients were 60.1 ± 9.4 and 40.9 ± 10.2 months, respectively. Mean OS times in the HR and RFA groups were 67.5 ± 15.4 and 51.1 ± 9.8 months (P = 0.671), respectively, and the mean DFS time in the HR group (74.1 ± 14.2 months) was longer than that in the RFA group (26.9 ± 9.2 months), but the difference was not significant (P = 0.076).

CONCLUSIONS
In patients who are not candidates for surgical treatment, RFA may be an alternative to HR.

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