In this study We examined the impacts of lower limit discontinuous negative pressing factor (INP) treatment for 1 hour multiple times every day for 12 weeks on the strolling distance of patients with irregular claudication (IC). 

Patients with IC were randomized to treatment with −40 mm Hg INP (treatment bunch) or −10 mm Hg INP (hoax control bunch). Agony free strolling distance (PWD) and maximal strolling distance (MWD) on a treadmill, resting and postexercise lower leg brachial file, resting and postischemic blood stream (plethysmography), and personal satisfaction (EQ-5D-5L and Vascuqol-6) were estimated at gauge and following 12 weeks of treatment. Both in general and for the gathering of patients with a PWD <200 m, no huge contrasts were found in the progressions in the resting and postexercise lower leg brachial record, resting and postischemic blood stream, or personal satisfaction boundaries between the two gatherings. 

Treatment with −40 mm Hg INP expanded the PWD contrasted and farce treatment in patients with IC. For the patients with a standard PWD of <200 m, an increment was found in both PWD and MWD contrasted and joke treatment.

Reference link- https://www.jvascsurg.org/article/S0741-5214(20)32281-3/fulltext