To analyze the treatment success rate (TSR = sum of cured or treatment completed) in the tuberculosis (TB) program for drug susceptible TB (DS-TB) of the “Centre Hospitalier Régional Spécialisé” in Macenta, Forest Region, Republic of Guinea.
This cohort study included patients starting treatment for DS-TB between 2010 and 2017. Data collection was part of the documentation for the national TB program. Descriptive analysis was applied to determine TSR in various patient groups. Further, we performed logistic regression to determine factors influencing TSR, in new and relapse cases versus all other previously treated cases. A subgroup analysis for only microbiologically confirmed pulmonary TB was added.
We included 3,969 patients. TSR increased from 68.3% in 2010 to 80.8% in 2017 (p 100 km) to the clinic and late drug refill.
TSR in the Forest Region of Guinea remains below the WHO goal of 90%. Reaching this target remains a challenge in rural areas with high early mortality and increased risk of loss to follow-up.

Copyright © 2021. Published by Elsevier Ltd.