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Recent aspects of uranium toxicology in medical geology.

Recent aspects of uranium toxicology in medical geology.
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Bjørklund G, Albert Christophersen O, Chirumbolo S, Selinus O, Aaseth J,


Bjørklund G, Albert Christophersen O, Chirumbolo S, Selinus O, Aaseth J, (click to view)

Bjørklund G, Albert Christophersen O, Chirumbolo S, Selinus O, Aaseth J,

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Environmental research 2017 04 26156() 526-533 pii S0013-9351(17)30500-5
Abstract

Uranium (U) is a chemo-toxic, radiotoxic and even a carcinogenic element. Due to its radioactivity, the effects of U on humans health have been extensively investigated. Prolonged U exposure may cause kidney disease and cancer. The geological distribution of U radionuclides is still a great concern for human health. Uranium in groundwater, frequently used as drinking water, and general environmental pollution with U raise concerns about the potential public health problem in several areas of Asia. The particular paleo-geological hallmark of India and other Southern Asiatic regions enhances the risk of U pollution in rural and urban communities. This paper highlights different health and environmental aspects of U as well as uptake and intake. It discusses levels of U in soil and water and the related health issues. Also described are different issues of U pollution, such as U and fertilizers, occupational exposure in miners, use and hazards of U in weapons (depleted U), U and plutonium as catalysts in the reaction between DNA and H2O2, and recycling of U from groundwater to surface soils in irrigation. For use in medical geology and U research, large databases and data warehouses are currently available in Europe and the United States.

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