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Recent research on nasal polyps includes an evaluation of the Sino-Nasal Outcome Test 22 questionnaire and a look at the mental impact of the condition.
Nasal polyps are soft, benign growths that form on the lining of the nose or sinuses. Common causes include asthma, chronic rhinosinusitis, and inflammation. Both medications and surgical procedures can be used to treat the condition.
Below is a review of recent research on nasal polyps, including in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).
1. SNOT-22 Questionnaire Assists With Treatment Selection
A longitudinal evaluation of the Sino-Nasal Outcome Test 22 (SNOT-22) questionnaire found it is effective for distinguishing, in patients with CRSwNP, which patients will respond quickly to monoclonal antibody therapy versus those who will have a low response or no response.
To read more, click here.
2. Blood Basophil Count Indicates Inflammation Severity in CRSwNP
In an analysis of primarily young adult patients with CRSwNP (aged 19-60 years; n=243), researchers found that blood basophil (P=0.016), lymphocyte (P<0.001), and monocyte (P=0.031) counts, as well as Lund-Mackay scores (P=0.025), were statistically different between age groups. The findings indicate a heterogeneous role of blood basophils in CRSwNP that supports their role as a marker of inflammation severity in CRSwNP.
To read more, click here.
3. Beyond Physical Symptoms: CRSwNP Impacts Mental Health
Researchers analyzed 200 adults with CRSwNP, 100 adults without CRSwNP (control group), and 50 caregivers of patients with CRSwNP. The team found that the burden of disease includes sleep impairment, absenteeism and presenteeism, stress, poor self-image, emotional distress, and challenges with treatment responsibilities, with sleep disruption being the most detrimental to quality of life. These burdens are in addition to the physical discomfort associated with the disease, study investigators noted.
To read more, click here.
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