There have been various incidents wherein the transient expression of Neurog3 has been able to commit itself for the intestines and their secretions which play a vital role in becoming enteroendocrine-biased progenitors and hence, they will be in the position to drive enteroendocrine differentiation. Therefore, what matters the most in such situations is to understand that any loss of Neurog3 is linked with the decrease in the efficiency of the intestine to secrete. Therefore, there have been various studies that have been conducted so far in order to understand that the mutant Neurog3 reporter is highly affecting the lining of the glands that secrete. The results highlighted the fact that the cells which have been derived from Neurog3 require a sort of goblet marker Muc2. there is a decrease of 53 percent in the number of secretions due to the changes code of the RNA cells and the secretions are affected due to the presence of Neurog3. This is true for not only the intestine but also other organs and glands which are available.

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