Thyroid hormones play an important role in systemic metabolism, although the link between thyroid dysfunction and the risk of type 2 diabetes is unknown. To determine the risk of type 2 diabetes in adulthood in adolescents with thyroid problems. National, population-based research of Israeli teenagers was evaluated prior to military enrollment from 1988 to 2007 and followed up on until December 31, 2016. There are 1 382 560 teenagers. Thyroid problems were diagnosed using current thyroid function testing. The information was connected to the Israeli National Diabetes Registry. During an 18.5-year average follow-up, 1.12 per cent of adolescents with thyroid problems were diagnosed with type 2 diabetes, compared to 0.77 per cent of adolescents without thyroid disorders. After controlling for gender, birth year, BMI, and sociodemographic factors, the hazard ratio (HR) for type 2 diabetes was 2.3 among individuals with thyroid problems. Diabetes risk was raised in both men and women, with or without obesity, and in the absence of other health problems, and was linked to several types of thyroid abnormalities. It was similarly comparable when type 2 diabetes was defined as being diagnosed at or before the age of 30. Thyroid problems identified in youth are a risk factor for both men and women developing type 2 diabetes at a young age.

Reference: https://academic.oup.com/jcem/article-abstract/106/9/e3426/6288474?redirectedFrom=fulltext