Here are what the editors at HealthDay consider to be the most important developments in Cardiology for September 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Hospital Admissions Not Related to COVID-19 Fell in Early 2020

WEDNESDAY, Sept. 30, 2020 (HealthDay News) — Non-COVID-19 hospital admissions decreased considerably with the onset of COVID-19, with declines generally similar across patient demographic subgroups from February to April 2020, according to a report published online Sept. 24 in Health Affairs.

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Disparities in CVD Burden Increasing Between Richest, Poorer

WEDNESDAY, Sept. 30, 2020 (HealthDay News) — There are substantial and increasing disparities in the prevalence of cardiovascular disease (CVD) among the highest-resource group and the remainder of the U.S. population, according to a study published online Sept. 25 in JAMA Network Open.

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Women With AMI-Cardiogenic Shock Treated Less Aggressively

TUESDAY, Sept. 29, 2020 (HealthDay News) — Among young adults with acute myocardial infarction-cardiogenic shock (AMI-CS), women are treated less aggressively and have higher in-hospital mortality than men, according to a study published online Sept. 29 in Circulation: Heart Failure.

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Outcomes of In-Hospital Cardiac Arrest Poor in COVID-19 Patients

MONDAY, Sept. 28, 2020 (HealthDay News) — None of 54 patients hospitalized with COVID-19 with in-hospital cardiac arrest who underwent cardiopulmonary resuscitation (CPR) survived to discharge, according to a research letter published online Sept. 28 in JAMA Internal Medicine.

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Private Health Plans Pay Hospitals 247 Percent of Medicare

MONDAY, Sept. 28, 2020 (HealthDay News) — During 2018, prices paid to hospitals by privately insured patients averaged 247 percent of what Medicare would have paid, according to a study from the RAND Corporation.

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Exposure to Maternal Gestational Diabetes Tied to Higher CVD Risk

MONDAY, Sept. 28, 2020 (HealthDay News) — Intrauterine exposure to maternal gestational diabetes is associated with an increased cardiovascular disease risk and risk factors in offspring up to age 35 years, according to a study published online Sept. 28 in CMAJ, the journal of the Canadian Medical Association.

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Hydroxychloroquine Tied to Heart Problems Prior to Pandemic

MONDAY, Sept. 28, 2020 (HealthDay News) — Real-world, pre-COVID-19 adverse events data show hydroxychloroquine (HCQ) and chloroquine (CQ) are associated with cardiovascular adverse events (CVAEs), according to a study published online Sept. 22 in the British Journal of Clinical Pharmacology.

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14 Novel Loci Identified for Abdominal Aortic Aneurysm

MONDAY, Sept. 28, 2020 (HealthDay News) — In a genome-wide association study (GWAS), published online Sept. 28 in Circulation, researchers identified 14 novel loci for abdominal aortic aneurysm (AAA).

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Metabolic Surgery May Cut Risk for Cardiovascular Events, Death

MONDAY, Sept. 28, 2020 (HealthDay News) — Metabolic surgery for patients with morbid obesity and pharmacologically treated hypertension is associated with a lower risk for major adverse cardiovascular events (MACE) and all-cause mortality versus individuals with hypertension from the general population, according to a study published online Sept. 15 in PLOS Medicine.

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Poorer Exercise Capacity Persists With Ventricular Septal Defects

FRIDAY, Sept. 25, 2020 (HealthDay News) — As they get older, patients with surgically closed or unrepaired congenital ventricular septal defects (VSDs) have poorer exercise capacity than their healthy peers, according to a study published online Sept. 23 in the Journal of the American Heart Association.

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Heavy Sugar-Sweetened Drink Intake Decreasing Overall in U.S.

THURSDAY, Sept. 24, 2020 (HealthDay News) — Overall, heavy sugar-sweetened beverage (SSB) intake is declining among adults and children, according to a study published online Sept. 24 in the Journal of the Academy of Nutrition and Dietetics.

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Major Adverse CV Event Risk Reduced With SGLT2 Inhibitors

THURSDAY, Sept. 24, 2020 (HealthDay News) — For individuals with type 2 diabetes, sodium glucose cotransporter 2 (SGLT2) inhibitors are associated with a reduced risk for cardiovascular events during short-term follow-up, according to a study published online Sept. 23 in The BMJ.

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Stroke ‘Alarm Clock’ Improves Acute Stroke Management Metrics

THURSDAY, Sept. 24, 2020 (HealthDay News) — Use of a stroke alarm clock demanding active feedback significantly improves management metrics for acute stroke, according to a study published online Sept. 24 in Stroke.

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Measures of Central Adiposity Linked to All-Cause Mortality

THURSDAY, Sept. 24, 2020 (HealthDay News) — Several indices of central adiposity, including waist circumference and body adiposity index, are associated with an increased risk for all-cause mortality, according to a review published online Sept. 23 in The BMJ.

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Guidelines Updated for Managing Dyslipidemia to Cut CVD Risk

THURSDAY, Sept. 24, 2020 (HealthDay News) — In a synopsis of the 2020 updated clinical practice guideline from the U.S. Department of Veterans Affairs and the U.S. Department of Defense, published online Sept. 22 in the Annals of Internal Medicine, recommendations are presented for the management of dyslipidemia to reduce cardiovascular disease (CVD) risk.

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Oral Steroids May Raise Risks for Diabetes, HTN, VTE in Children

WEDNESDAY, Sept. 23, 2020 (HealthDay News) — Children with current glucocorticoid exposure have increased risks for diabetes mellitus, hypertension, and venous thromboembolism (VTE), according to a study published online Sept. 9 in the American Journal of Epidemiology.

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Fewer Women Aware of Heart Disease as Leading Cause of Death

WEDNESDAY, Sept. 23, 2020 (HealthDay News) — From 2009 to 2019, there was a decrease in awareness among U.S. women that heart disease is the leading cause of death (LCOD) among women, according to a special report from the American Heart Association, published online Sept. 21 in Circulation.

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Adverse Pregnancy Outcomes Tied to Later Atherosclerotic CVD

TUESDAY, Sept. 22, 2020 (HealthDay News) — Adverse pregnancy outcomes (APOs), particularly hypertensive disorders of pregnancy and low birth weight, may be risk factors for atherosclerotic cardiovascular disease (ASCVD) in older women, according to a study published online Sept. 16 in JAMA Cardiology.

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Rates of Recurrent MI Declined Among U.S. Women and Men

TUESDAY, Sept. 22, 2020 (HealthDay News) — From 2008 to 2017, there were decreases in the rates of recurrent myocardial infarction (MI), recurrent coronary heart disease (CHD) events, heart failure hospitalization, and all-cause mortality in both men and women, according to a study published online Sept. 21 in Circulation.

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Air Pollution May Raise Stroke Risk With Atrial Fibrillation

TUESDAY, Sept. 22, 2020 (HealthDay News) — Exposure to air pollution may increase the risk for ischemic stroke in patients with atrial fibrillation (AF), according to a study published online Sept. 15 in JAMA Network Open.

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Individuals With Autism at Risk for Other Health Conditions

MONDAY, Sept. 21, 2020 (HealthDay News) — Individuals with autism have increased health risks even when considering lifestyle factors, according to a study published online Sept. 9 in Autism.

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Impact of Psoriasis Explored for Hospital Outcomes of Acute MI

MONDAY, Sept. 21, 2020 (HealthDay News) — Myocardial infarction (MI) events may occur earlier in life in patients with psoriasis, which in turn may affect hospital outcomes, according to a study published online Sept. 11 in the Journal of the American Heart Association.

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Hostility Predicts Mortality in Acute Coronary Syndrome

MONDAY, Sept. 21, 2020 (HealthDay News) — For patients with acute coronary syndrome (ACS), hostility predicts all-cause mortality but not recurrence, according to a study published online Sept. 14 in the European Journal of Cardiovascular Nursing.

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EPA, DHA Supplementation Linked to Reduced Risk for MI, CHD

THURSDAY, Sept. 17, 2020 (HealthDay News) — Supplementation with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is associated with a reduced risk for myocardial infarction (MI) and coronary heart disease (CHD) events, according to a meta-analysis published online Sept. 17 in the Mayo Clinic Proceedings.

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Study Suggests Smoking Causes Fatal Subarachnoid Hemorrhage

THURSDAY, Sept. 17, 2020 (HealthDay News) — Smoking seems to have a causal role in subarachnoid hemorrhage (SAH), according to a study published online Sept. 17 in Stroke.

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Transient Orthostatic Hypotension Common in Parkinson Disease

THURSDAY, Sept. 17, 2020 (HealthDay News) — Transient orthostatic hypotension (tOH) is common in Parkinson disease (PD), according to a study published online Sept. 16 in Neurology.

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Pacemaker Need Higher in Patients With Type 2 Diabetes

WEDNESDAY, Sept. 16, 2020 (HealthDay News) — The need for pacemakers is higher among patients with type 2 diabetes than the general population, according to a study published online Sept. 4 in Diabetes Care.

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Severely Obese Heart Donors Not Tied to Adverse Transplant Outcomes

WEDNESDAY, Sept. 16, 2020 (HealthDay News) — Severe obesity in organ donors is not associated with adverse heart transplant outcomes, according to a study published online Sept. 16 in Circulation: Heart Failure.

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Better Cardiovascular Health Linked to Lower Incident HTN

WEDNESDAY, Sept. 16, 2020 (HealthDay News) — For adults without hypertension, better cardiovascular health as measured by Life’s Simple 7 (LS7) is associated with a lower risk for incident hypertension, according to a study published online Sept. 16 in the Journal of the American Heart Association.

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Many Doctors Misinformed About Nicotine’s Risks

WEDNESDAY, Sept. 16, 2020 (HealthDay News) — Most doctors hold misperceptions about the risks of nicotine, according to research published online Sept. 1 in the Journal of General Internal Medicine.

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Early Age at Menarche Tied to Worse Cardiovascular Health

TUESDAY, Sept. 15, 2020 (HealthDay News) — Early menarche in women is associated with worse cardiovascular health, according to a study published online Sept. 7 in Menopause.

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Factor V Activity Significantly Increased in Severe COVID-19

TUESDAY, Sept. 15, 2020 (HealthDay News) — Factor V activity is significantly increased in patients with severe COVID-19, according to a study published online Aug. 24 in the American Journal of Hematology.

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Lipid-Rich Necrotic Core Linked to Psoriasis Severity

TUESDAY, Sept. 15, 2020 (HealthDay News) — For patients with psoriasis, lipid-rich necrotic core (LRNC) is associated with psoriasis severity and cardiovascular risk factors and is reduced for those patients receiving biologic therapy, according to a study published online Sept. 15 in Circulation: Cardiovascular Imaging.

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NIH Launches Clinical Trials of Antithrombotics for COVID-19

MONDAY, Sept. 14, 2020 (HealthDay News) — Two of three planned adaptive phase 3 clinical trials evaluating the safety and effectiveness of varying types of blood thinners to treat adults diagnosed with COVID-19 have launched, according to an announcement by the National Institutes of Health (NIH).

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Coronary Artery Calcium Score IDs Coronary Heart Disease Risk

MONDAY, Sept. 14, 2020 (HealthDay News) — Coronary artery calcium (CAC) risk score is a better predictor of coronary heart disease (CHD) than stroke, according to a study published online Aug. 18 in Circulation: Cardiovascular Imaging.

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Smokeless Tobacco Poses Global Health Burden

FRIDAY, Sept. 11, 2020 (HealthDay News) — Smokeless tobacco (ST) is used across the globe and poses a major public health threat, according to a review published online Aug. 12 in BMC Medicine.

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Rates of Ambulatory Heart Failure Steady From 2001 to 2016

FRIDAY, Sept. 11, 2020 (HealthDay News) — Rates of ambulatory heart failure remained steady in the United States between 2001 and 2016, according to a study published online Sept. 2 in JAMA Cardiology.

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Future Cardiovascular Event Risk Up With High BP in Young Adults

FRIDAY, Sept. 11, 2020 (HealthDay News) — Young adults with elevated blood pressure have increased risk of subsequent cardiovascular events, according to a meta-analysis published online Sept. 9 in The BMJ.

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Controlled BP Down Among U.S. Adults With HTN After 2013–2014

THURSDAY, Sept. 10, 2020 (HealthDay News) — The prevalence of controlled blood pressure (BP) among U.S. adults with hypertension increased from 1999-2000 to 2007-2008 then decreased after 2013 to 2014, according to a study published online Sept. 9 in the Journal of the American Medical Association.

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Widespread Avoidance of Medical Care Found Due to COVID-19 Concerns

THURSDAY, Sept. 10, 2020 (HealthDay News) — There was widespread reporting of avoidance of medical care due to COVID-19-related concerns in June 2020, according to research published in the Sept. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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CDC: Nearly 800 U.S. Children Have Developed COVID-19-Related Condition

THURSDAY, Sept. 10, 2020 (HealthDay News) — There have been 792 confirmed cases in the United States of a rare condition in children that is linked to COVID-19, the U.S. Centers for Disease Control and Prevention said Wednesday.

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Moderate, Heavy Drinking Linked to Increased BP, HTN in T2DM

THURSDAY, Sept. 10, 2020 (HealthDay News) — For individuals with type 2 diabetes, moderate and heavy drinking are associated with an increased risk for elevated blood pressure, stage 1 hypertension, and stage 2 hypertension, according to a study published online Sept. 9 in the Journal of the American Heart Association.

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CYP2C19 Genotyping May Aid Antiplatelet Prescribing

WEDNESDAY, Sept. 9, 2020 (HealthDay News) — Genotyping may provide some clinical benefit in prescribing antiplatelet therapies for patients undergoing percutaneous coronary intervention (PCI), according to a study published in the Aug. 25 issue of the Journal of the American Medical Association.

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Early Therapy for Rheumatoid Arthritis May Slow Heart Disease

WEDNESDAY, Sept. 9, 2020 (HealthDay News) — Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in the Annals of the Rheumatic Diseases.

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High Coronary Artery Calcium + Diabetes Even Riskier for Women

TUESDAY, Sept. 8, 2020 (HealthDay News) — For patients with diabetes, coronary artery calcium (CAC) predicts cardiovascular disease (CVD) and total mortality more strongly in women than men, according to a study published online Aug. 17 in Diabetes Care.

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Cardiovascular Health Tied to Lower Risk for Eye Diseases

THURSDAY, Sept. 3, 2020 (HealthDay News) — Ideal cardiovascular health is associated with lower odds for ocular diseases, according to a study published Aug. 19 in The American Journal of Medicine.

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Invasive Treatment Tied to Better Outcomes in Elderly With NSTEMI

THURSDAY, Sept. 3, 2020 (HealthDay News) — Invasive management is beneficial for patients with non-ST elevation myocardial infarction (NSTEMI) aged 80 years or older, according to a study published online Aug. 27 in The Lancet.

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Early Body Mass Index Tied to Cardiometabolic Risk at Age 11 to 12

THURSDAY, Sept. 3, 2020 (HealthDay News) — Toddlers who are overweight or obese have higher cardiometabolic risk scores at 11 to 12 years of age, according to a study published in the Aug. 1 issue of Pediatrics.

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Deaths From Atrial Fibrillation Declined From 1972 to 2015

WEDNESDAY, Sept. 2, 2020 (HealthDay News) — There has been a decline in deaths related to atrial fibrillation (AF) over the last 45 years, according to a study published online Aug. 11 in The BMJ.

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High-Intensity Lifestyle Treatment Beneficial for Obesity in Underserved

WEDNESDAY, Sept. 2, 2020 (HealthDay News) — For an underserved primary care population, a high-intensity lifestyle-based treatment program for obesity results in significant weight loss at 24 months, according to a study published in the Sept. 3 issue of the New England Journal of Medicine.

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VA/DoD Issue Guideline for Diagnosis, Management of HTN

WEDNESDAY, Sept. 2, 2020 (HealthDay News) — In a synopsis of the 2020 U.S. Department of Veterans Affairs/U.S. Department of Defense clinical practice guideline, published online Sept. 1 in the Annals of Internal Medicine, recommendations are presented for the diagnosis and management of hypertension.

Clinical Practice Guideline

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Nonpsychotic Mental Disorder in Teens Linked to Later MI Risk

TUESDAY, Sept. 1, 2020 (HealthDay News) — Having a nonpsychotic mental disorder in adolescence is associated with increased risk of subsequent myocardial infarction, with stress resilience partially attenuating the association, according to a study presented at the European Society of Cardiology Congress 2020: The Digital Experience, held virtually from Aug. 29 to Sept. 1.

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ADA Updates Guideline for Pharmacotherapy of T2DM

TUESDAY, Sept. 1, 2020 (HealthDay News) — In a 2020 American Diabetes Association clinical guideline, published online Sept. 1 in the Annals of Internal Medicine, recommendations are presented for the pharmacologic treatment of adults with type 2 diabetes.

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