Human adenoviruses (HAdV) are known to cause a wide range of diseases including acute respiratory infections, conjunctivitis, and acute gastroenteritis. In this study, we aimed to determine the serotypes of HAdV in patients with influenza-like illness in the Philippines from 2006-2012 and to describe the demographic and epidemiological characteristics of patients who tested positive with HAdV.
Between 2006-2012, the Philippine National Influenza Centre detected HAdV in 1,294 samples from patients with influenza-like-illness (ILI). Serotype determination was done in select samples using microneutralization, PCR and sequencing methods.
A total of eight serotypes were identified (HAdV 1-7, 11), with HAdV-2 (27.8%) and HAdV-3 (27.8%) being the most prevalent. Majority of HAdV infections were found in children below 5 years of age (79.9%).
The identification of HAdV circulating serotypes may serve as guide for designing disease intervention and control strategies and will provide important information regarding the contribution of this virus in respiratory infections, particularly in children, which remain to be a public health burden in the Philippines.
Copyright © 2022. Published by Elsevier Ltd.
Serotype Identification of Human Adenoviruses Associated with Influenza-Like Illnesses in the Philippines from 2006 to 2012 by Microneutralization and Molecular Techniques.
