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Sister Mary Joseph’s nodule as initial pancreatic cancer manifestation.

Sister Mary Joseph’s nodule as initial pancreatic cancer manifestation.
Author Information (click to view)

Vallejo Bernad C, Casamayor Franco MC, Hakim Alonso S,


Vallejo Bernad C, Casamayor Franco MC, Hakim Alonso S, (click to view)

Vallejo Bernad C, Casamayor Franco MC, Hakim Alonso S,

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Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 2016 12 23109() doi 10.17235/reed.2016.4479/2016
Abstract

We report the case of an 85-year-old female patient who presented with umbilical pain associated with an indurated growth, the whole being apparently consistent with incarcerated umbilical hernia, which prompted an urgent surgical procedure for its removal. The pathology study revealed dermal infiltration by a malignancy. Gland tumor cells expressed an immunohistochemical profile initially consistent with a pancreatic origin. In view of these findings a CT scan was performed, which revealed a pancreatic tail tumor as well as multiple hepatic metastasis. Skin metastasis is a rare sign usually reflecting a carcinoma of unknown origin. Umbilical skin metastasis, called Sister Mary Joseph´s nodule, reflect an intra-abdominal tumor, being pancreatic cancer strange.

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