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Species-specific Clinical Characteristics of Human Coronavirus Infection among Otherwise Healthy Adolescents and Adults.

Species-specific Clinical Characteristics of Human Coronavirus Infection among Otherwise Healthy Adolescents and Adults.
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Bouvier M, Chen WJ, Arnold JC, Fairchok MP, Danaher PJ, Lalani T, Malone L, Mor D, Ridoré M, Burgess TH, Millar EV,


Bouvier M, Chen WJ, Arnold JC, Fairchok MP, Danaher PJ, Lalani T, Malone L, Mor D, Ridoré M, Burgess TH, Millar EV, (click to view)

Bouvier M, Chen WJ, Arnold JC, Fairchok MP, Danaher PJ, Lalani T, Malone L, Mor D, Ridoré M, Burgess TH, Millar EV,

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Influenza and other respiratory viruses 2018 01 19() doi 10.1111/irv.12538
Abstract

Human coronavirus (HCoV) is a known cause of influenza-like illness (ILI). In a multi-site, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12% of subjects were PCR-positive for HCoV. The distribution of species was as follows: HCoV-OC43 (34%), HCoV-229E (28%), HCoV-NL63 (22%), and HCoV-HKU1 (16%). We did not observe species-specific differences in the clinical characteristics of HCoV infection, with the exception of HCoV-HKU1, for which the severity of gastrointestinal symptoms trended higher on the fourth day of illness. This article is protected by copyright. All rights reserved.

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