A review of more than 125,000 patients on stable statin therapy suggests that nearly half (44%) of those who had their treatment intensified were non-adherent to their treatment. When compared with adherent patients, those who were not were 30% more likely to have had their statin therapy intensified. Those with statin therapy intensification were more likely to be younger, female, and have coronary artery disease, diabetes, hypertension, dyslipidemia, stroke, peripheral arterial disease, heart failure, or depression.

Abstract: American Journal of Cardiology, November 15, 2012.