Pharmacies should proactively offer naloxone, a drug that blocks or reverses the effects of overdose, to patients taking opioid medications through universal opt-out strategies in an effort to get the life-saving drug into the hands of more people who need it, according to a new study out of Boston Medical Center (BMC).
The US Department of Health and Human Services named expanding access to the rescue medication naloxone (known also by the brand name Narcan) one of three main strategies to address the opioid crisis. Research has found educating and providing naloxone to people who are at risk of witnessing or experiencing an overdose leads to a 30-50 percent decrease in opioid death rates.
After conducting a series of eight focus groups in two states with over 60 pharmacists, pain patients, current and former drug users, and family members of people who use opioids, researchers found consistent support for an “opt-out” model of offering naloxone in the pharmacy, rather than the current model that has people asking for it at the pharmacy counter–where too few do. The opt-out model universally offers naloxone to those obtaining opioid prescriptions or those with identifiable medication-related risks, such as patients taking high doses of opioids for pain or for opioid use disorder, or those who are co-prescribed opioids and sleep aids or anxiety drugs. It would also target those who pick up such prescriptions for their family members.
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The study is published in the Journal of American Pharmacists Association and is part of the larger MOON study, led by Dr. Green and others at BMC and in collaboration with researchers at Boston University, Lifespan Hospitals of Rhode Island and the University of Rhode Island. The three-year project is funded by the Agency for Healthcare Research & Quality, which is working with local pharmacies in Massachusetts and Rhode Island to determine the best way to provide naloxone in the pharmacy setting.