When compared with antiepileptic drug (AED) therapy alone, using respective surgery plus AED therapy appears to result in a lower probability of seizures after 2 years follow-up in patients with newly intractable, disabling mesial temporal lobe epilepsy. Results from a small study indicated that 73% of patients who received AED therapy plus surgery were seizure free at 2 years, compared with a 0% rate for patients who received only AED therapy.

Abstract: JAMA, March 7, 2012.