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Synovial sarcoma mimicking benign peripheral nerve sheath tumor.

Synovial sarcoma mimicking benign peripheral nerve sheath tumor.
Author Information (click to view)

Larque AB, Bredella MA, Nielsen GP, Chebib I,


Larque AB, Bredella MA, Nielsen GP, Chebib I, (click to view)

Larque AB, Bredella MA, Nielsen GP, Chebib I,

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Skeletal radiology 2017 07 08() doi 10.1007/s00256-017-2710-x
Abstract
OBJECTIVE
To assess the radiographic and clinicopathologic features of synovial sarcoma of the nerve that were clinically or radiologically interpreted as benign peripheral nerve sheath tumor.

MATERIALS AND METHODS
Five patients with synovial sarcoma arising from the peripheral nerve and interpreted clinically and radiologically as peripheral nerve sheath tumors were identified. Clinicopathologic and imaging features were evaluated.

RESULTS
There were three females and two males, ranging in age from 28 to 50 (mean 35.8) years. Most patients (4/5) complained of a mass, discomfort or pain. MR images demonstrated a heterogeneous, enhancing, soft tissue mass contiguous with the neurovascular bundle. On histologic examination, most tumors were monophasic synovial sarcoma (4/5). At the time of surgery, all tumors were noted to arise along or within a peripheral nerve. All patients were alive with no evidence of disease with median follow-up of 44 (range 32-237) months. For comparison, approximately 775 benign peripheral nerve sheath tumors of the extremities were identified during the same time period.

CONCLUSIONS
Primary synovial sarcoma of the nerve can mimic peripheral nerve sheath tumors clinically and on imaging and should be included in the differential diagnosis for tumors arising from peripheral nerves.

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