Misinterpreting Benefits of Cancer Screenings

According to results from a national survey, improved survival and increased detection of cancer with screenings are mistakenly interpreted by most primary care physicians (PCPs) as evidence that screening saves lives. When presented with irrelevant evidence, 69% of PCPs recommended a test, compared with 23% when presented with relevant evidence. Nearly half (47%) stated incorrectly that detecting more cancer cases in screened versus unscreened patients proves that screening saves lives. Abstract: Annals of Internal Medicine, March 6,...
Could New Blood Test Detect Cancer?

Could New Blood Test Detect Cancer?

A blood test that could revolutionize the way doctors detect and treat cancer is one step closer to becoming available. Johnson & Johnson has teamed up with Massachusetts General Hospital to develop and market a blood test that can detect a single cancer cell among a billion healthy cells in a person’s blood. While it might take at least 5 years before the test is widely available, it is a step closer to personalized medicine. Some cancer cells can break away from the origin and travel throughout the peripheral blood. This test uses a microchip resembling a lab slide, which is  covered in 78,000 tiny posts coated with antibodies that bind to tumor cells. Only cancer cells will “stick” to these posts. Studies of the chip have been published in the journals Nature, the New England Journal of Medicine and Science Translational Medicine. The earlier cancer is detected, the more hope there is for a cure. Many cancers are undetectable until they reach a late stage, while others, such as breast cancer, require screening and radiation exposure. Typically, many cancers are diagnosed through needle biopsies. These may not always provide enough of a sample to determine what genes or pathways control a tumor’s growth. Some patients only live long enough to try one or two treatments, so a test that identifies cancer cells in the blood and can gauge success sooner or dictate treatment could give patients more options. Initially the test would be used for those who had cancer in the past or are in the process of being treated, and it would complement existing tests like x-rays, CT scans, and...