ESC 2021 Heart Failure

A novel analysis of DAPA-HF investigated the efficacy of dapagliflozin on ventricular arrhythmia (VA), resuscitated cardiac arrest (RCA), and sudden death. The results showed a significantly reduced likelihood for the composite...

The GUIDE-HF trial, presented in a Hot Line Session and simultaneously published in The Lancet, showed benefits of hemodynamic-guided heart failure (HF) management with an implantable device in reducing HF hospitalization [1,2]....

An American trial investigated the potential of valsartan in slowing the course of disease in hypertrophic cardiomyopathy (HCM). The results showed a significantly positive influence on relative cardiac remodeling in the...

The randomized controlled STEP trial revealed that lowering the systolic blood pressure (SBP) to below 130 mmHg in patients over 60 years led to a 26% reduction of adverse cardiovascular (CV) events [1]. A target SBP below 130...

EMPEROR-Preserved proved to be a landmark trial in heart failure research. It demonstrated a clinically meaningful benefit of 21% reduction in the primary composite outcome as well as positive results in secondary outcomes with...

Investigators used a Web-based recording system, as well as face-to-face regional benchmark analysis and educational meetings, in the BLITZ-HF prospective study to evaluate and improve adherence to heart failure (HF)...

With data lacking on acute coronary syndrome (ACS) in patients with heart failure (HF), researchers examined the characteristics and outcomes of non-ST elevation ACS (NSTACS) in patients with and without a prior medical history...

With sodium-glucose co-transporter 2 (SGLT-2) inhibitors becoming increasingly relevant for the treatment and prevention of heart failure (HF), study investigators sought to assess various SGLT-2 inhibitors in patients with...

To evaluate the cardiovascular (CV) benefits of sodium-glucose co-transporter 2 (SGLT-2) inhibitors according to 1) patient history of heart failure (HF) and 2) severity of left ventricular ejection fraction (LVEF) reduction in...

To examine outcomes in patients with chronic kidney disease, or CKD, with and without type 2 diabetes by history of HF at baseline, researchers assessed data on 4,304 patients—including 468 with a diagnosis of HF at...