Conference Highlights: ISET 2010

The International Symposium on Endovascular Therapy, or ISET, held its 2010 annual meeting from January 17-21in Hollywood, Florida. The features below highlight some of the news emerging from the meeting. For more information on these items and other research that was presented, go to Can A Blood Test Identify Endoleaks? The Particulars: Ruptured abdominal aortic aneurysms (AAAs) kill more than 13,000 Americans every year. Endovascular aneurysm repair (EVAR) is less invasive than open surgical repair of AAAs, but a downside is that about 10% of such repairs result in endoleaks. To monitor for endoleaks, patients undergo CT scans at 3, 6, and 12 months after EVAR and yearly thereafter. Data Breakdown: A study of AAA patients who had an endoleak and a simple blood test found elevated concentrations of a blood protein called matrix metalloproteinase-9 (MMP-9). Researchers determined that MMP-9 concentrations of 55.18 or greater helped to identify endoleaks with both high sensitivity and specificity. Results must be confirmed by a prospective clinical validation trial. Take Home Pearls: A blood test appears to be capable of detecting endoleaks after EVAR for AAAs. Use of this test may help prevent up to 90% of follow-up CT scans. Gender Differences in Treatment of Blocked Leg Arteries The Particulars: Narrowed and blocked leg arteries are a common symptom of peripheral arterial disease (PAD). About 8 million Americans have PAD, which can cause pain while walking. In extreme cases, these blocked leg arteries can lead to gangrene, lower-extremity amputations, or death. Data Breakdown: A retrospective study reviewed the use of endovascular therapy for blocked leg arteries. After 2 years, 46% of treated...