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Tenofovir disoproxil fumarate/emtricitabine fits for all as appropriate HIV-1 preexposure prophylaxis?

Tenofovir disoproxil fumarate/emtricitabine fits for all as appropriate HIV-1 preexposure prophylaxis?
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Taramasso L, Riccardi N, Del Puente F, Bruzzone B, Ripamonti D, D'ambrosio B, Viscoli C, Di Biagio A,


Taramasso L, Riccardi N, Del Puente F, Bruzzone B, Ripamonti D, D'ambrosio B, Viscoli C, Di Biagio A, (click to view)

Taramasso L, Riccardi N, Del Puente F, Bruzzone B, Ripamonti D, D'ambrosio B, Viscoli C, Di Biagio A,

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AIDS research and human retroviruses 2017 11 22() doi 10.1089/AID.2017.0112

Abstract

Pre-exposure prophylaxis (PrEP) with TDF/FTC significantly reduces the risk for HIV-1 transmission, but, to date, nobody knows if PrEP can still be useful in case of viruses harboring resistances to TDF/FTC or if alternative antiretroviral drugs might be rather proposed in selected cases. We promote the debate by describing a case of an acute infection with multi-resistant HIV that occurred in a young girl who started a relationship with a HIV-infected partner who had a known multi-resistant HIV.

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