This study aimed to analyze the micronutrients and heavy metals concentrations between subjects with the term and preterm birth. 

A cross-sectional study was conducted in Cipto Mangunkusumo Hospital and Budi Kemuliaan Hospital, Jakarta, Indonesia. Subjects were divided into term and preterm birth groups.

A total of 51 pregnant women participated in this study. Term group had higher concentration of maternal serum AtRA, higher placental concentration of manganese 0.99 μg/g versus 0.42 ± 0.18 μg/g, p <0.001, iron, copper 2.96 ± 1.80 μg/g versus 1.62 μg/g, p 0.019, zinc 58.34 μg/g versus 28.41 μg/g, p 0.011, selenium, AtRA 21.7 ± 10.69 ng/g versus 0.7 ng/g, p <0.001, and 25(OH)D 75.84 ± 45.12 ng/g versus 18.00 ng/g, p <0.001, lower placental concentration of mercury and lead, and higher cord blood concentration of copper 32.20 μg/dL versus 20.60 μg/dL, p 0.006 and AtRA . 

Preterm birth is associated with lower micronutrient concentrations that play a role in the antioxidant and higher mercury and lead engagements.