mosquitoes are important vectors for a number of human pathogens including the Zika, dengue, and chikungunya viruses. Capable of displacing populations, this mosquito adapts to cooler environments which increases its geographical range and transmission potential. There are limited control strategies for mosquitoes which is likely attributed to the lack of comprehensive biological studies on this emerging vector. To fill this void, here using RNAseq we characterized mRNA expression profiles at 34 distinct time points throughout development providing the first high-resolution comprehensive view of the developmental transcriptome of this worldwide human disease vector. This enabled us to identify several patterns of shared gene expression among tissues as well as sex-specific expression patterns. To illuminate the similarities and differences with , a related human disease vector, we also performed a comparative analysis between the two developmental transcriptomes, identifying life stages where the two species exhibit similar and distinct gene expression patterns. These findings provide insights into the similarities and differences between and mosquito biology. In summary, the results generated from this study should form the basis for future investigations on the biology of and provide a gold mine resource for the development of transgene-based vector control strategies.Copyright © 2020, G3: Genes, Genomes, Genetics.
March 12, 2020
The effect of dietary nitrate on exercise capacity in chronic kidney disease a randomized Controlled pilot study.
October 22, 2020
Cardiology on the cutting edge: updates from the European Society of Cardiology (ESC) Congress 2020.
October 22, 2020
August 22, 2014
- ACC 2020The American College of Cardiology decided to cancel ACC.20/WCC due to COVID-19, which was scheduled to take place March 28-30 in Chicago. However, ACC.20/WCC Virtual Meeting continues to release cutting edge science and practice changing updates for cardiovascular professionals on demand and free through June 2020.
- CROI 2020Every year, CROI hosts some of the world's leading experts in HIV research, who come to present exciting new data and drive forward the field of HIV/AIDS research. This year, due to COVID-19, CROI held their meeting virtually.