Asphyxia is the second leading cau­se of neonatal death in the world. The indi­ca­tor for the diagnosis of asphyxia in newborns is the APGAR score. APGAR score at the fifth minute of life correlated with the asphyxia deg­ree. This study was done with the purpose to estimate how great the effect of asphyxia on neonatal death based on the results of some previous studies.

This was a systematic and meta-analysis study. The articles used in this study were obtained from several databases. The articles were selected using the PICO model. The po­pulation of this study was neonatal with inter­ven­tion in the form of asphyxia, comparison, and outcome in the form of death. These articles were collected for 1 month. The articles included in this study were full-text articles with a cross-sectional study design. The articles were collected using PRISMA flow diagrams. The articles were ana­lyzed using the Review Manager 5.3 application.

The findings of the study concluded that 6 articles were reviewed in this study. This study showed that asphyxia increas­­ed the risk of neonatal death.