This states that As part of efforts to prevent the escalation of SARS-CoV-2 transmission, the US Centers for Disease Control and Prevention issued nationwide stay-at-home recommendations in the United States on March 15, 2020.1 Also, states across the country issued varying degrees of physical distancing measures, including restrictions on transportation and movement, school closures, and business closures. Since then, studies have shown, using mathematical and epidemiological models, that such distancing measures likely reduced transmission of COVID-19.2, 3 Others have shown the effect of these measures on the incidence of other viral acute respiratory infections (ARIs) such as influenza.4, 5 However, only a few community surveillance studies were ongoing before the stay-at-home orders and can show the effect of these measures on a population already under ARI surveillance. Here, we use data from a prospective college cohort under ARI surveillance to assess the impact of the physical distancing measures on the rate of ARI-related symptoms.

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