For a study, researchers sought to examine the impact of care packages on the occurrence of surgical site infections (SSIs). The search was carried out between February and May 2021, utilizing the databases PubMed, CINAHL, SCOPUS, Cochrane, and EMBASE. Studies that employed systematic review methods were in English had a quantitative design, and investigated the utility of care packages for SSI prevention were included. A total of 35 papers matched the inclusion criteria, with 26 supplying data suitable for meta-analysis. Data were extracted using a predesigned extraction program, and RevMan was used for analysis (Cochrane, London, UK). Evidence-based librarianship was used to assess quality. 

The average sample size was 7,982 (median, 840) people. There was a statistically significant difference in SSI incidence favoring the use of a care bundle (SSI incidence 4%, 703/17,549 in the care bundle group vs. 7%, 1,157/17,162 in the standard care group). The odds ratio was 0.55 (95% CI, 0.41–0.73; P<.00001), indicating that the care bundle group had a 45% lower risk of developing SSI. The overall mean validity score was 84% (SD, 0.04%). The findings showed that introducing care packages lowered the incidence of SSI. However, because there was clinically significant variance in the content of and adherence to care bundles, further study using standardized care bundles is required to corroborate this conclusion.