The microbiome is described as the collection of microorganisms, their genomes, and their interactions in a certain ecological niche. Atopic dermatitis is a multifactorial chronic inflammatory skin condition that causes skin dryness and itching. Comorbidities such as allergic rhinoconjunctivitis and asthma are frequently linked with it. Today, culture-free approaches for defining microorganisms and their genomes that may be both harmful and helpful to their host have been developed. There are indications that microorganisms on the skin and in the stomach may impact the development of atopic dermatitis. 

Antiseptic treatment has been used for decades, but today, with the aid of conventional culture-based techniques and contemporary metagenomics, we are beginning to realise that targeted dysbiosis treatment may one day become part of an integrated therapeutic plan.