Advertisement

 

 

The mouse viral outgrowth assay: avatars for the detection of HIV-1 reservoirs.

The mouse viral outgrowth assay: avatars for the detection of HIV-1 reservoirs.
Author Information (click to view)

Metcalf Pate KA, Blankson JN,


Metcalf Pate KA, Blankson JN, (click to view)

Metcalf Pate KA, Blankson JN,

Advertisement

Retrovirology 2017 11 2114(1) 52 doi 10.1186/s12977-017-0376-z

Abstract

Sensitive assays are needed for the detection of residual viral reservoirs in HIV-1-infected subjects on suppressive combination antiretroviral therapy regimens to determine whether eradication strategies are effective. Mouse viral outgrowth assays have recently been developed and have the potential to be more sensitive than traditional in vitro quantitative viral outgrowth assays. In this article we describe these assays and review several studies that have used them to measure the latent reservoir.

Submit a Comment

Your email address will not be published. Required fields are marked *

seventeen + 9 =

[ HIDE/SHOW ]