Journal of diabetes investigation 2017 01 27() doi 10.1111/jdi.12633
To explore the relationships between periodontitis and microvascular complications as well as glycemic control in type 2 diabetic patients.
MATERIALS AND METHODS
This multi-center hospital-based cross-sectional study included 620 patients with type 2 diabetes. We compared the prevalence and severity of periodontitis between patients with ≥1 microvascular complication and those without microvascular complications. We also compared the prevalence and severity of periodontitis among patients with different degrees of glycemic control.
After adjusting for confounding factors, multiple logistic regression analysis showed that the severity of periodontitis was significantly associated with the number of microvascular complications (OR 1.3; 95%Cl, 1.1-1.6), HbA1c ≥8.0% (64 mmol/mol) (OR 1.6; 95%Cl, 1.1-2.3), and older age (≥50 years) (OR 1.7; 95%Cl, 1.1-2.6). However, the prevalence of periodontitis was not significantly associated with the number of microvascular complications, but was associated with male sex, high HbA1c (≥8.0% [64 mmol/mol]), older age (≥40 years), longer duration of diabetes (≥15 years), and fewer teeth (≤25). Furthermore, propensity score matching for age, sex, diabetes duration, and HbA1c showed that the incidence of severe periodontitis was significantly higher among patients with microvascular complications than among those without microvascular complications (P < 0.05). CONCLUSIONS
The number of microvascular complications is a risk factor for more severe periodontitis in patients with type 2 diabetes, while poor glycemic control is a risk factor for increased prevalence and severity of periodontitis. This article is protected by copyright. All rights reserved.