The incidence of viral infections, like Hepatitis B (HBV), Hepatitis C (HCV), and HIV is not routinely screened in patients with newly diagnosed cancer, but experts believe new-onset cancer could increase the risk of these viral diseases. This study aims to determine the prevalence of HBV, HCV, and HIV in patients with newly diagnosed cancer.

This multicenter prospective cohort study included a total of 3,050 eligible patients (median age 60.6 years, 60.4% female) with newly diagnosed cancer (diagnosed within 120 days). The patients were evaluated for the incidence of viral infections, with the primary endpoint being the presence of HBV, HCV, and HIV infections.

Among eligible patients, HBV infection occurred in 197 patients (6.5%), chronic HBV in 19 patients (0.6%), HCV in 71 patients (2.4%), and HIV in 34 patients (1.1%). Of the patients with viral infections, 8 with chronic HBV, 22 with HCV, and 2 with HIV were diagnosed during the study. Besides, no identifiable risk factors were discovered in 4, 23, and 7 patients, respectively, with chronic HBV, HCV, and HIV.

The findings concluded that most patients with newly diagnosed cancer and HBV, HCV, or HIV did not exhibit any identifiable risk factors.