PONV is among the most common unpleasant and distressing adverse events following surgery under general anesthesia. FESS is a common otolaryngology procedure. Prevention of PONV and early recovery are cost-effective.
This study aimed to evaluate the prophylactic effect of bilateral endoscopic injection of lidocaine with epinephrine in the SPG on PONV in patients undergoing FESS.
One hundred patients with chronic rhinosinusitis undergoing general anesthesia for FESS were enrolled in this double-blind, placebo-controlled study. Patients were randomized to receive an injection of 2 mL of 2% lidocaine with epinephrine or 2 mL of saline at the end of surgery.
The two groups were comparable in characteristic and intraoperative features. In general, the incidence of PONV after FESS was 36%. The average time that patients can tolerate oral feeding was 3.4 h after surgery. Endoscopic SPG injection with lidocaine significantly reduced the incidence of vomiting and PONV.
The study concluded that SPG injection with lidocaine at the end of surgery is a safe, non-invasive, and useful technique in reducing early PONV in endoscopic sinus surgery patients.
Reference: https://journals.sagepub.com/doi/full/10.1177/1945892418782235
