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Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders.

Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders.
Author Information (click to view)

Kim HP, Lim H, Kwon YS,


Kim HP, Lim H, Kwon YS, (click to view)

Kim HP, Lim H, Kwon YS,

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Biomolecules & therapeutics 2016 12 16() doi 10.4062/biomolther.2016.187
Abstract

Acute bronchitis and chronic obstructive pulmonary diseases (COPD) are essentially lung inflammatory disorders. Various plant extracts and their constituents showed therapeutic effects on several animal models of lung inflammation. These include coumarins, flavonoids, phenolics, iridoids, monoterpenes, diterpenes and triterpenoids. Some of them exerted inhibitory action mainly by inhibiting the mitogen-activated protein kinase pathway and nuclear transcription factor-κB activation. Especially, many flavonoid derivatives distinctly showed effectiveness on lung inflammation. In this review, the experimental data for plant extracts and their constituents showing therapeutic effectiveness on animal models of lung inflammation are summarized.

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