Time-restricted eating (TRE), limiting energy intake to 8 hours followed by fasting for 16 hours (16:8 TRE), is associated with a reduction in cardiovascular disease (CVD) risk among older breast cancer survivors (BCS), according to a research letter published in JACC: CardioOncology. Amy A. Kirkham, PhD, and colleagues conducted a single-arm feasibility study to examine adherence, safety, and preliminary efficacy of 8 weeks of 16:8 TRE on CVD risk among 22 BCS (aged 60 and older). Participants adhered to at least 16- hours of fasting for a median of 98% of prescribed days. Calorie intake changed by a median of -450 kcal, representing a 22% relative reduction. There was no change noted in fat-free mass. At 8 weeks, the median Framingham CVD risk decreased from 10.9% to 8.6% (-15% relative change). No significant change was seen in the modifiable Framingham components overall. Decreases were seen in mean MRI-derived visceral adipose tissue, bioelectrical impedance analysis-derived whole-body fat mass, and body mass.

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