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Towards an ultra-rapid smartphone- connected test for infectious diseases.

Towards an ultra-rapid smartphone- connected test for infectious diseases.
Author Information (click to view)

Turbé V, Gray ER, Lawson VE, Nastouli E, Brookes JC, Weiss RA, Pillay D, Emery VC, Verrips CT, Yatsuda H, Athey D, McKendry RA,


Turbé V, Gray ER, Lawson VE, Nastouli E, Brookes JC, Weiss RA, Pillay D, Emery VC, Verrips CT, Yatsuda H, Athey D, McKendry RA, (click to view)

Turbé V, Gray ER, Lawson VE, Nastouli E, Brookes JC, Weiss RA, Pillay D, Emery VC, Verrips CT, Yatsuda H, Athey D, McKendry RA,

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Scientific reports 2017 09 207(1) 11971 doi 10.1038/s41598-017-11887-6

Abstract

The development is reported of an ultra-rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detect HIV in a finger prick of blood within 10 seconds (sample-in-result-out). The disposable quartz biochip, based on microelectronic components found in every consumer smartphone, is extremely fast because no complex labelling, amplification or wash steps are needed. A pocket-sized control box reads out the SAW signal and displays results electronically. High analytical sensitivity and specificity are found with model and real patient blood samples. The findings presented here open up the potential of consumer electronics to cut lengthy test waiting times, giving patients on the spot access to potentially life-saving treatment and supporting more timely public health interventions to prevent disease transmission.

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