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Treatment of cutaneous angiosarcoma of the scalp and face in the Chinese patients: local experience at a regional hospital in Hong Kong.

Treatment of cutaneous angiosarcoma of the scalp and face in the Chinese patients: local experience at a regional hospital in Hong Kong.
Author Information (click to view)

Chow TL, Kwan WW, Kwan CK,


Chow TL, Kwan WW, Kwan CK, (click to view)

Chow TL, Kwan WW, Kwan CK,

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Hong Kong medical journal = Xianggang yi xue za zhi 2018 01 12() doi 10.12809/hkmj176813
Abstract
INTRODUCTION
Angiosarcoma is a rare aggressive sarcoma that occurs mostly in the skin of the head and neck in the elderly population. The optimal management is dubious and most studies are from Caucasian populations. We aimed to find out the treatment and outcome of this disease in Chinese patients.

METHODS
Data of patients with histopathologically verified cutaneous angiosarcoma of the head and neck during December 1997 to September 2016 were retrieved from our cancer registry. The demographic data, clinicopathological information, modality of treatment, and outcomes were reviewed.

RESULTS
During the study period, 17 Chinese patients were treated. Their median age was 81 years. The tumours were present in the scalp only (n=11), face only (n=4), or both scalp and face (n=2). Only two patients had distant metastases. The modalities of treatment were surgery (n=6), surgery and adjuvant radiotherapy (n=1), palliative radiotherapy (n=5), or palliative chemotherapy (n=3). The remaining two patients refused any treatment initially. Of the seven patients treated surgically, there were four local and two regional recurrences. The median time to relapse was 7.5 months. Overall, 16 patients had died; causes of death were disease-related in 12 while four other patients died of inter-current illnesses. One patient was still living with the disease. The median overall survival was 11.1 months and the longest survival was 42 months.

CONCLUSION
The outcome of angiosarcoma in our series is poor. A high index of suspicion is mandatory for prompt diagnosis. Adjuvant radiotherapy is recommended following surgery. The benefit and role of systemic treatment in various combinations with surgery or radiotherapy requires further study.

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