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Two-year clinical outcomes in stable angina and acute coronary syndrome after percutaneous coronary intervention of left main coronary artery disease.

Two-year clinical outcomes in stable angina and acute coronary syndrome after percutaneous coronary intervention of left main coronary artery disease.
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Hyun DY, Jeong MH, Sim DS, Jeong YA, Cho KH, Kim MC, Kim HK, Jeong HC, Park KH, Hong YJ, Kim JH, Ahn Y, Kang JC,


Hyun DY, Jeong MH, Sim DS, Jeong YA, Cho KH, Kim MC, Kim HK, Jeong HC, Park KH, Hong YJ, Kim JH, Ahn Y, Kang JC, (click to view)

Hyun DY, Jeong MH, Sim DS, Jeong YA, Cho KH, Kim MC, Kim HK, Jeong HC, Park KH, Hong YJ, Kim JH, Ahn Y, Kang JC,

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The Korean journal of internal medicine 2016 Oct 18() doi 10.3904/kjim.2014.373
Abstract
Background/Aims
This study appraised the long term clinical outcomes of patients treated with percutaneous coronary intervention (PCI) for unprotected left main coronary artery (ULMCA) disease. There are limited data regarding long-term clinical outcomes after PCI for ULMCA disease.

Methods
From 2001 to 2011, a total of 448 patients who underwent PCI for ULMCA disease and had 2-year clinical follow-up, were analyzed. The study patients were divided into two groups: group I (stable angina pectoris [SAP], n = 60, 48 men, 62 ± 10 years) and group II (acute coronary syndrome [ACS], n = 388, 291 men, 64 ± 10 years). We evaluated clinical and angiographic characteristics and major adverse cardiac events (MACE) during 2-year clinical follow-up.

Results
Mean age of studied patients was 64 ± 10 years with 339 male patients. Average stent diameter was 3.6 ± 0.4 mm and stent length was 19.7 ± 6.3 mm. Stent implantation techniques and use of intravascular ultrasound guidance were not different between two groups. In-hospital mortality was 0% in group I and 7% in group II (p = 0.035). One-month mortality was 0% in group I and 7.7% in group II (p = 0.968). Two-year survival rate was 93% in the group I and 88.4% in the group II (p = 0.921). Predictive factors for 2-year MACE were hypertension, Killip class ≥ 3, and use of intra-aortic balloon pump by multivariate analysis.

Conclusions
Although in-hospital mortality rate was higher in ACS than in SAP, clinical outcomes during 2-year clinical follow-up were similar between SAP and ACS after PCI of ULMCA.

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