We aimed in the given trial to explore the quality of life after six years of treatment in the HYPO-RT-PC trial. The HYPO-RT-PC trail gave a clear distinction between the fractionated radiotherapy and ultra-hypofractionated radiotherapy. All these radiotherapy techniques were efficient with prostate cancer and made treatment more efficient. However, the Ultra-hypofractionation was not very much inferior to the conventional one as it provided a five-year failure-free survival.

Up till 2015, more than1200 patients came and enrolled in this trial. On the basis of division in groups, one can see the difference in the patient’s metabolic activities with the time passing by. Up to 6 long years, the 7 out of 10 problems occurring in the bowel moment was more evidently seen in the ultra-hypofractionated radiotherapy. There were no statistically proven evident differences in the proportions of patients those who had clinically relevant acute urinary symptoms or problems (total 14 items) and sexual functioning between the two treatment groups at the end of radiotherapy.

Although there was very much high toxicity in the body in the case of ultra-hypofractionation when compared to the conventional techniques speaking of the long term treatment, it is a very well-tolerated technique. These findings support ultra-hypofractionation radiotherapy for use. 

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(20)30581-7/fulltext