Advertisement

 

 

Use of a trigger tool to detect adverse drug reactions in an emergency department.

Use of a trigger tool to detect adverse drug reactions in an emergency department.
Author Information (click to view)

de Almeida SM, Romualdo A, de Abreu Ferraresi A, Zelezoglo GR, Marra AR, Edmond MB,


de Almeida SM, Romualdo A, de Abreu Ferraresi A, Zelezoglo GR, Marra AR, Edmond MB, (click to view)

de Almeida SM, Romualdo A, de Abreu Ferraresi A, Zelezoglo GR, Marra AR, Edmond MB,

Advertisement

BMC pharmacology & toxicology 2017 11 1518(1) 71 doi 10.1186/s40360-017-0177-y
Abstract
BACKGROUND
Although there are systems for reporting adverse drug reactions (ADR), these safety events remain under reported. The low-cost, low-tech trigger tool method is based on the detection of events through clues, and it seems to increase the detection of adverse events compared to traditional methodologies. This study seeks to estimate the prevalence of adverse reactions to drugs in patients seeking care in the emergency department.

METHODS
Retrospective study from January to December, 2014, applying the Institute for Healthcare Improvement (IHI) trigger tool methodology for patients treated at the emergency room of a tertiary care hospital.

RESULTS
The estimated prevalence of adverse reactions in patients presenting to the emergency department was 2.3% [CI95 1.3% to 3.3%]; 28.6% of cases required hospitalization at an average cost of US$ 5698.44. The most common triggers were hydrocortisone (57% of the cases), diphenhydramine (14%) and fexofenadine (14%). Anti-infectives (19%), cardiovascular agents (14%), and musculoskeletal drugs (14%) were the most common causes of adverse reactions. According to the Naranjo Scale, 71% were classified as possible and 29% as probable. There was no association between adverse reactions and age and sex in the present study.

CONCLUSIONS
The use of the trigger tool to identify adverse reactions in the emergency department was possible to identify a prevalence of 2.3%. It showed to be a viable method that can provide a better understanding of adverse drug reactions in this patient population.

Submit a Comment

Your email address will not be published. Required fields are marked *

eight + two =

[ HIDE/SHOW ]