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Use of corticosteroids is not associated with repeated vertebroplasty or kyphoplasty within one year after the surgery in patient older than 50 years.

Use of corticosteroids is not associated with repeated vertebroplasty or kyphoplasty within one year after the surgery in patient older than 50 years.
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Kao FC, Hsu YC, Wu CH, Wang CB, Tu YK, Liu PH,


Kao FC, Hsu YC, Wu CH, Wang CB, Tu YK, Liu PH, (click to view)

Kao FC, Hsu YC, Wu CH, Wang CB, Tu YK, Liu PH,

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Acta orthopaedica et traumatologica turcica 2017 10 31() pii S1017-995X(17)30025-1
Abstract
OBJECTIVE
The aim of this study was to investigate whether corticosteroid use increases the incidence of repeated PVP or kyphoplasty patients older than 50 years.

METHODS
This study enrolled the data of 2,753 eligible patients from the Taiwan National Health Insurance Research Database who were exposed to systemic corticosteroids for at least 3 months during the first year preceding the first PVP or kyphoplasty. These steroid users were matched 1:1 in age, sex, and the index date of surgery with non-user controls during the enrollment period. All patients were followed for 1 year after the first PVP or kyphoplasty. The incidence of repeated PVP or kyphoplasty was compared between the steroid users and controls. A Cox proportional hazards model was developed to account for multiple confounding factors.

RESULTS
The number of patients receiving repeated PVP or kyphoplasty was 233 (8.46%) and 205 (7.45%) in the corticosteroid and control groups, respectively. The Cox proportional hazards model revealed no association between corticosteroid use and repeated PVP or kyphoplasty.

CONCLUSIONS
Systemic corticosteroid use for longer than 3 months is not associated with repeated PVP or kyphoplasty within one year of surgery in patient older than 50 years old.

LEVEL OF EVIDENCE
Level III, Therapeutic study.

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