Willingness to Take, Use of, and Indications for Pre-Exposure Prophylaxis among Men Who Have Sex with Men – 20 U.S. Cities, 2014.

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Hoots BE, Finlayson T, Nerlander L, Paz-Bailey G, ,

Hoots BE, Finlayson T, Nerlander L, Paz-Bailey G, , (click to view)

Hoots BE, Finlayson T, Nerlander L, Paz-Bailey G, ,


Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 6 9() pii

 Pre-exposure prophylaxis (PrEP) is an effective prevention tool for people at substantial risk of acquiring HIV. To 1) monitor the current state of PrEP use among men who have sex with men (MSM), we report on willingness to use PrEP and PrEP utilization, and 2) assess whether the MSM sub-populations at highest risk for infection have indications for PrEP according to the 2014 clinical guidelines, we estimated indications for PrEP for MSM by demographics.

 We analyzed data from the 2014 cycle of the National HIV Behavioral Surveillance system among MSM who tested HIV-negative in NHBS and were currently sexually active. Adjusted prevalence ratios and 95% confidence intervals were estimated from log-linked Poisson regression with generalized estimating equations to explore differences in willingness to take PrEP, PrEP use, and indications for PrEP.

 Whereas over half of MSM said they were willing to take PrEP, only about 4% reported using PrEP. There was no difference in willingness to take PrEP between black and white MSM. PrEP use was higher among white compared to black MSM and among those with greater education and income levels. Young, black MSM were less likely to have indications for PrEP compared to young MSM of other races/ethnicities.

 Young, black MSM, despite being at high risk of HIV acquisition, may not have indications for PrEP under the current guidelines. Clinicians may need to consider other factors besides risk behaviors such as HIV incidence and prevalence in sub-groups of their communities when considering prescribing PrEP.

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