Women suffer more frequently and more severely from pollen and food allergies and therefore also from asthma. Firstly, female sex hormones increase the risk and symptoms of asthma and allergies and, secondly, hormone preparations such as the contraceptive pill play a role. These factors should be given more consideration than was previously the case. Erika Jensen-Jarolim from MedUni Vienna’s Institute of Pathophysiology and Allergy Research stresses this point on the occasion of International Women’s Day on 8 March.
Up until the age of 10, boys are more likely to suffer from allergies and asthma and to have more severe symptoms. But the increased production of the sex hormone estrogen associated with the onset of sexual maturity and puberty means that girls become much more susceptible. Jensen-Jarolim explains: “Oestrogens cause inflammatory cells, such as the mast cells, for example, to react more sensitively to allergens. Conversely, the male hormone testosterone seems to exert a kind of protective function.”
This phenomenon accompanies women through the waves of hormone production in their respective life phases — from their first period to the taking of contraceptives, pregnancy through to hormonal replacement therapy at the menopause. In addition to that, they become more sensitive to environmental pollutants, especially smoking.
Nowadays, taking hormones is almost unavoidable because of life and family planning and also to avoid falling hormone levels, which play a significant role in the development of osteoporosis, for example. “Such hormone treatments can trigger hypersensitivities, which, on top of that, are characterised by atypical symptomatology,” explains Jensen-Jarolim. These atypical symptoms include migraines, joint pain, eczema, worsening of acne and breathing difficulties. “We still do not pay enough attention to these links in the interaction between allergology and gynaecology.” Hormone treatments are also playing an increasing role in transgender medicine and must be borne in mind.