Jonathan Friedberg, MD, discusses the 2017 ASH Meeting on Hematologic Malignancies (MHM) and the value of the “How I Treat” format for practicing clinicians. During the meeting’s “How I Treat” presentations, speakers present cutting-edge scientific data that can be translated into new strategies for diagnosis and treatment, showcase their own evidence-based treatment approaches, and address what to do in cases where there is no data.