Allergy & Immunology | Physician's Weekly
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Allergy & Immunology

Current and future management of the young child with early onset wheezing

Aug 02, 2021

In this review, researchers examine current thinking in regard to published recommendations for the management of preschool-aged children with recurrent wheezing, identifying gaps in our understanding...

Strategies to alter the natural history of childhood asthma

Aug 02, 2021

Asthma varies significantly in incidence and severity over the lifetime. The objective of this study is to examine new research on the drivers of the natural history of asthma in children, as well as ...

Management of preschool recurrent wheezing and asthma

Aug 02, 2021

The aim of this study is to evaluate the latest data on the administration of pre-school children with wheeze and asthma and propose a phénotype-based strategy to child management. Recent studies hav...

The effect of obesity, weight gain, and weight loss on asthma inception and control

Aug 02, 2021

Obesity raises the risk of asthma and asthma morbidity, according to an increasing body of research. The study examines current clinical data showing a causal connection between obesity and asthma, as...

Microbes, allergic sensitization, and the natural history of asthma

Aug 02, 2021

Understanding the variables that contribute to asthma development in childhood is critical for creating primary or secondary preventive measures. This article will cover current information on the dev...

Assessment of population immunity to measles in Ontario, Canada

Aug 02, 2021

Measles was eradicated in Canada in 1998. Researchers conducted a sero-epidemiology research in Ontario, Canada, to assess population immunity to measles and identify populations at increased risk of ...

Cost-effectiveness of workplace vaccination against measles

Aug 02, 2021

One of the most contagious infectious illnesses is measles. The measles vaccination, which was launched in Italy in 1979, is extremely successful in avoiding the disease. Italy ranked second in the EU...

Reporting quality of systematic reviews of interventions aimed at improving vaccination coverage

Aug 02, 2021

Systematic reviews have grown in importance for influencing clinical practice and policy; however, little is known regarding the reporting features and quality of SRs of interventions to enhance vacci...

Assessing the methodological quality of systematic reviews of interventions aimed at improving vaccination coverage

Aug 02, 2021

Systematic reviews (SRs) are the foundation of evidence-based medicine, but there is no gold standard for judging their methodological excellence. Although the AMSTAR tool is widely used to assess the...

Knowledge, awareness, attitude, and practice of health-care professionals toward hepatitis B disease and vaccination

Aug 02, 2021

Since health-care professionals (HCPs) are at a high risk of unintentional exposure to hepatitis B virus (HBV) from infected patients, the purpose of this study was to evaluate HCPs' knowledge, awaren...

The joint effects of clinically relevant depressive symptoms and cardiovascular risk factors on incident cardiovascular disease among older adults in the community.

Aug 02, 2021

To determine if there is a synergistic effect between clinically relevant depressive symptoms and cardiovascular risk factors that disproportionately increases the risk of cardiovascular disease (CVD)...

Risk factors for irreversible airway obstruction after infant bronchiolitis.

Aug 02, 2021

Increasing evidence shows that environmental factors in childhood play a role in development of irreversible airway obstruction. We evaluated early-life and preschool-age risk factors for irreversible...

A cross-sectional survey of cannabis use by people with MS in Oregon and Southwest Washington.

Aug 02, 2021

Evidence supports that cannabinoids reduce self-reported spasticity and neuropathic pain in people with MS (PwMS), and legal access to cannabis for medical and recreational use continues to rise. Howe...

School-Age Obese Asthmatic Children have Distinct Lung Function Measures From Lean Asthmatics and Obese Children.

Aug 02, 2021

The lung functions of children with obese asthma seem to be distinct from those of obese children or lean asthmatics. To measure baseline lung function, exercise-induced bronchoconstriction (EIB), an...

IL-25R circulating fibrocytes are increased in asthma and correlate with fixed airflow limitation.

Aug 02, 2021

IL-25 is a T helper (Th) type -2 cytokine implicated in the pathogenesis of asthma. Fibrocytes are progenitor cells that can migrate into circulation and inflamed bronchial epithelium.We aim to test t...

Knockdown of NOVA1 inhibits inflammation and migration of asthmatic airway smooth muscle cells to regulate PTEN/Akt pathway by targeting PTBP1.

Aug 02, 2021

NOVA1 (neuro-oncological ventral antigen 1) is a neuron specific RNA binding protein, belonging to the Nova family, which plays an important role in various diseases. However, the role of NOVA1 in chi...

Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction.

Aug 02, 2021

Viola yedoensis Makiho (VY, Violaceae) is a well-known medicinal herb in Chinese medicine, which is traditionally used to treat inflammation-related disorders, including allergic skin reactions. Altho...

Respiratory syncytial virus nonstructural protein 1 breaks immune tolerance in mice by downregulating Tregs through TSLP-OX40/OX40L-mTOR axis.

Aug 02, 2021

Respiratory syncytial virus (RSV) infection in early life is associated strongly with the subsequent development and exacerbation of asthma, however, the mechanism is still ambiguous. In this study, w...

Topical treatment with mastic (resin from Pistacia lentiscus) elicits anti-inflammatory and anti-pruritic responses by modulating keratinocyte activation in a mouse model of allergic dermatitis.

Aug 02, 2021

As the number of patients with skin allergies, including atopic dermatitis, has increased rapidly, therapeutic options such as anti-IL-31 antibody and Janus kinase inhibitor have been developed recent...

The choice of biologics in patients with severe chronic rhinosinusitis with nasal polyps.

Aug 02, 2021

Patients with severe CRSwNP represent an unmet clinical need in terms of recurrent disease despite current medical and surgical therapy. Targeting type 2 inflammatory cytokines (IL4/5/13) appears to b...